Transfusion of blood and blood components (i.e. RBCs, platelets, plasma, and cryoprecipitate) which became a routine practice for more than half a century is one of the most common medical procedures performed in the developed world. However, the decision to transfuse or not to transfuse is one of the more complex decisions made by medical practitioners.
Blood and blood component transfusion is one of the cornerstones of supportive treatment for cancer patients. transfusion therapy is required because of cancer-induced myelosuppression, chemotherapy-induced myelosuppression, chronic illness and surgical or medical blood loss.
An assessment of the value of transfusion is the first step in optimizing transfusion practices. to assess the impact of transfusion practice on patient outcomes, knowledge about transfusion strategy is required. clinical practice guidelines are necessary for the practice of evidence-based medicine, which optimizes patient care and improves patient outcomes. In this topic, the impacts, the hazards, indications and guidelines in transfusion therapy for pediatric cancer patients well be discussed.