Cancer is emerging as a public health problem among an array of non-communicable diseases.The common cancers that affect women are breast, cervix uteri, colo-rectum,ovary and corpus uteri. Breast cancer (BC) is common cancer and the leading cause of cancer death in females worldwide. About half of the BCs and 60% of the deaths are estimated to occur in economically developing countries.In most of the urban registries in India, BC is the commonest cancer with the highest incidence of nearly 50 per105women in Trivandrum. The factors that contribute to the international variation in BCincidence rates are largely due to the differences in reproductive and hormonal factors and the availability of early detection services.Colorectal cancer (CRC) is the 2ndmost common cancer in women worldwide. The burden of CRC has risen rapidly in some economically developed Asian countries like Japan, South Korea, and Singapore. Nationally, the highest CRC incidence rates are observed in Trivandrum and its incidence has been increasing. Presently,it is the 5th common cancer among women in Trivandrum. The major risk factors include certain dietary practices and family history of cancer. Individuals with a family history of colon cancer, especially if more than one relative has had the disease, are at increased risk of CRC.Cervix uteri cancer is the 3rdmost common cancer affecting women worldwide and the most common cancer among women in several less developed countries. Presently it is the 2ndcommon cancer in India. During the past few decades, incidence of this cancer has been decreased in India. Significant declines in cervix uteri cancer are likely due to changes in marriage and family planning methods, supported by underlying improvements in education and socioeconomic status. Over the years in spite of decreasing incidence of this cancer, the gynecologic cancers have increased in India and are contributing about 30% of total cancers among women in India. Among these,ovary and corpus uteri cancers are the major contributors.Ovarian cancer has emerged as one of the common malignancies affecting women in India and is the 4th common cancer in Trivandrum. A steady increase has been observed in ovarian cancer incidence in several cancer registries including Trivandrum in India. More than 50% of women with ovarian cancer are under the age of 50 years. The risk of it increases in women who have ovulated more over their lifetime. Other risk factors include hormone therapy after menopause, fertility medication, and obesity. Factors that decrease risk include hormonal birth control, tubal ligation, and breastfeeding.Corpus uteri cancers are most common in western countries but are becoming more common in Asia. Nationally, the highest corpus uteri cancer incidence rates are observed in Trivandrum and its incidence has been increasing. Presently, it is the 5th common cancer among women in Trivandrum. Ninety percent of women with corpus uteri cancer are over the age of 50 years. The risk factors for corpus uteri cancer include obesity, diabetes mellitus, breast cancer, use of tamoxifen, nulliparity, late menopause and high levels of estrogen. Results based on the burden, trends in incidence & mortality,risk factors based on epidemiologic studies and survival of breast, colorectal, cervix uteri, ovary and corpus uteri cancers will be presented.